Job Description

Principal Scientist, Cell Therapy In Vivo Pharmacology Principal Scientist, Cell Therapy In Vivo Pharmacology Apply locations Seattle - WA - US time type Full time posted on Posted 4 Days Ago job requisition id R1589895 Working with Us Challenging. Meaningful. Life-changing. Those aren’t words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it. You’ll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams rich in diversity. Take your career farther than you thought possible. Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. The In Vivo Pharmacology team in the Cell Therapy Thematic Research Center has an opening for a highly collaborative and creative Principal Scientist with a dedication to discovery and development of novel engineered immune effector cell therapeutics for the treatment of cancer and other chronic diseases. The successful candidate will have a strong immunology background, experience with a broad range of tumor models, and a desire to lead functional workstreams from early stages/target concept through to IND filing. This position is ideal for a motivated and interactive scientist who is passionate about cell therapy and has a proven track record working across highly matrixed teams to drive key decisions for drug discovery and development. Position Responsibilities In the role as a Principal Scientist within the In Vivo Pharmacology Team, the ideal candidate will: Lead functional workstreams on highly matrixed cell therapy research project teams from target concept to IND. Mentor/supervise pharmacology team members to support in vivo experimentation, including planning and directing lab research. Possess broad experience in the development and execution of tumor models, including syngeneic and xenograft models, and/or T cell-driven immune response models. Demonstrate expertise in multi-parameter flow cytometry (10-plus colors), immune cell functional assays (e.g. proliferation, cytokine production, cytotoxicity), and the field of cellular immunology. Independently author study reports, technical protocols, publications and documents to support regulatory and patent submissions, demonstrating broad experience in scientific writing. Present complex concepts to a range of audiences including governance and departmental meetings. Apply advanced technical knowledge to guide the development of cutting-edge immune cell therapies. Excel in a fast-paced team environment, meet deadlines, and prioritize work on multiple projects while fostering open and productive scientific communication and collaboration. Basic Qualifications: Bachelor’s Degree with 8+ years of academic and/or industry experience. Or Master’s Degree with 6+ years of academic and/or industry experience. Or Ph.D. or equivalent advanced degree in the Life Sciences with 4+ years of academic and/or industry experience. Preferred Qualifications: Ph.D. or equivalent advanced degree in Immunology or related field. 6+ years of academic and industry experience. Experience with preclinical assessment of therapeutic candidates including cell-based therapies, immunotherapies, and drug combination studies. Knowledge of pharmacokinetic and pharmacodynamic models to evaluate candidate therapeutics. Familiarity with gene editing technologies and delivery methods (e.g., adeno-associated viral vectors, non-viral delivery, CRISPR gene editing). Ability to write and manage IACUC protocols, own compliance with these and other protocols, and identify potential gaps. Track record of successful internal and external scientific collaborations. Experience supervising technical staff to lead early-stage projects. The starting compensation for this job is a range from $153,680 - $186,200, plus incentive cash and stock opportunities (based on eligibility). The starting pay rate takes into account characteristics of the job, such as required skills and where the job is performed. Final, individual compensation will be decided based on demonstrated experience. #LI-Onsite If you come across a role that intrigues you but doesn’t perfectly line up with your resume, we encourage you to apply anyway. You could be one step away from work that will transform your life and career. Uniquely Interesting Work, Life-changing Careers With a single vision as inspiring as “Transforming patients’ lives through science,” every BMS employee plays an integral role in work that goes far beyond ordinary. Each of us is empowered to apply our individual talents and unique perspectives in an inclusive culture, promoting diversity in clinical trials, while our shared values of passion, innovation, urgency, accountability, inclusion, and integrity bring out the highest potential of each of our colleagues. #J-18808-Ljbffr Bristol-Myers Squibb

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